Table 2.

Predicted Value Information of Different Variable Parameters for Disease Severity and Prognosis in COVID-19 Patients

Variables	Cut off value	Sensitivity	Specificity	PPV	NPV	Accuracy	Youden index
Predicting disease severity
sTREM-1, pg/mL	105	0.79	0.61	0.51	0.85	0.74	0.40
PCT, ng/mL	0.115	0.66	0.72	0.54	0.81	0.70	0.38
CRP, mg/L	65.9	0.39	0.88	0.63	0.74	0.72	0.27
HGB, g/L	108	0.31	0.76	0.40	0.68	0.61	0.07
Albumin, g/L	31.7	0.49	0.86	0.66	0.76	0.73	0.35
D-dimer, mg/L	248	0.64	0.72	0.56	0.78	0.69	0.36
eGFR, mL/min/1.73 m²	93.2	0.79	0.41	0.41	0.79	0.54	0.21
LCR	0.00879	0.37	0.95	0.78	0.75	0.75	0.32
CAR	0.224	0.92	0.40	0.44	0.91	0.58	0.32
Predicting prognosis
sTREM-1, pg/mL	198	0.60	0.87	0.41	0.94	0.86	0.47
PCT, ng/mL	0.105	0.8	0.61	0.24	0.95	0.63	0.41
CRP, mg/L	35.7	0.87	0.66	0.28	0.97	0.69	0.53
HGB, g/L	107	0.47	0.79	0.25	0.91	0.75	0.26
Albumin, g/L	31.7	0.67	0.81	0.34	0.94	0.79	0.47
D-dimer, mg/L	425	0.67	0.73	0.30	0.93	0.72	0.40
eGFR, mL/min/1.73 m²	79.9	0.73	0.63	0.23	0.94	0.64	0.36
LCR	0.0187	0.8	0.72	0.31	0.96	0.73	0.52
CAR	0.86	0.93	0.64	0.29	0.98	0.68	0.57
Combined Model	0.0951	0.93	0.77	0.42	0.98	0.80	0.70

Abbreviations: PPV, Positive predictive value; NPV, Negative predictive value; sTREM, soluble Triggering Receptors Expressed on Myeloid Cell; PCT, Procalcitonin; CRP, C-reactive protein; HGB, Hemoglobin; eGFR, estimated glomerular filtration rate; LCR, Lymphocyte-to- C-reactive protein ratio; CAR, C-reactive protein-to-albumin ratio.