Table 2. Association between neck circumference measured during pregnancy and glucose levels and markers of insulin resistance in the postpartum among women with obesity/overweight with and without GDM.
Fasting glucose (mg/dL) | 2-hour glucose (mg/dL) | HbA1c (%) | Fasting insulin (µUI/mL) | Log HOMA-IR | TyG index | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | |
Crude | 1.22 (0.30-2.13) | 0.010 | 3.09 (0.27-5.91) | 0.032 | 0.05 (0.02-0.08) | 0.001 | 0.64 (0.15-1.14) | 0.011 | 0.07 (0.02-0.11) | 0.006 | 0.03 (0.008-0.05) | 0.008 |
Model 1 | 1.33 (0.43-2.24) | 0.004 | 3.16 (0.47-5.84) | 0.022 | 0.05 (0.02-0.08) | 0.002 | 0.71 (0.20-1.22) | 0.006 | 0.07 (0.03-0.12) | 0.003 | 0.03 (0.009-0.05) | 0.006 |
Model 2 | 1.42 (0.29-2.55) | 0.015 | 2.48 (-0.79-5.75) | 0.136 | 0.52 (0.1-0.09) | 0.006 | 0.50 (-0.11-1.17) | 0.107 | 0.05 (-0.00-0.11) | 0.072 | 0.02 (-0.006-0.04) | 0.138 |
Model 3 | 0.90 (-0.26 – 2.07) | 0.128 | 1.08 (-2.31-4.47) | 0.529 | 0.04 (-0.00-0.07) | 0.060 | 0.55 (-1.01-1.21) | 0.096 | 0.05 (-0.01-0.12) | 0.085 | 0.01 (-0.011-0.04) | 0.259 |
Linear regression analysis. Model 1, adjusted for age, family history of diabetes, and number of pregnancies. Model 2, Model 1 plus pregestational body mass index and weight gain during pregnancy. Model 3, Model 2 plus gestational diabetes.