Table 1. Baseline characteristics and clinical outcomes.

	N *	All patients (N = 2340)	Study A (N = 363)	Study B (N = 622)	Study C (N = 1355)
Age, years	2340	13 (10; 18)	12 (9; 14)	12 (10; 13)	16 (10; 25)
Sex male	2340	1403 (60)	195 (54)	412 (66)	796 (59)
Illness day at enrolment	2340
1		310 (13)	59 (16)	7 (1)	244 (18)
2		848 (36)	150 (41)	155 (25)	543 (40)
3		1137 (49)	114 (31)	455 (73)	568 (42)
4		45 (2)	40 (11)	5 (1)	0 (0)
Serotype	2340
DENV-1		1264 (54)	233 (64)	410 (66)	621 (46)
DENV-2		373 (16)	48 (13)	130 (21)	195 (14)
DENV-3		252 (11)	80 (22)	82 (13)	90 (7)
DENV-4		451 (19)	2 (1)	0 (0)	449 (33)
Immune status	2340
Probable primary		474 (20)	134 (37)	124 (20)	216 (16)
Probable secondary		1619 (69)	219 (60)	464 (75)	936 (69)
Indeterminate		247 (11)	10 (3)	34 (5)	203 (15)
Plasma leakage	2288	353 (15)	43 (13)	177 (29)	133 (10)
Missing		52	39	13	0
Illness day of plasma leakage	327
3		2 (1)	0 (0)	0 (0)	2 (2)
4		71 (22)	12 (30)	35 (23)	24 (18)
5		107 (33)	12 (30)	50 (32)	45 (34)
6		105 (32)	12 (30)	49 (32)	44 (33)
7		42 (13)	4 (10)	20 (13)	18 (14)
Missing		26	3	23	0
Severe dengue	2340	65 (3)	6 (2)	40 (6)	19 (1)
Illness day of severe dengue	65
3		2 (3)	0 (0)	2 (5)	0 (0)
4		13 (20)	0 (0)	12 (30)	1 (5)
5		24 (37)	2 (33)	16 (40)	6 (32)
6		20 (31)	4 (67)	7 (18)	9 (47)
7		6 (9)	0 (0)	3 (8)	3 (16)

Summary statistics are number of patients (%) or median (25th; 75th percentiles).

DENV: dengue virus.

^*N represents the number of patients with available data (i.e., without missing data).