Table 1.

Patient characteristics and laboratory measurements

	n (%) or median [IQR]
Patient characteristics
Age (years)	52 [40; 63]
Gender: male/female	15 (75) / 5 (25)
Weight (kg)	79 [71; 106]
Height (m)	1.77 [1.69; 1.85]
BMI (kg/m²)	25 [22; 33]
28-day mortality	10 (50)
SAPS II	78 [69; 90]
Renal replacement therapy
CVVHD	14 (70)
CVVHDF (post-dilution)	6 (30)
Blood flow (ml/min)	100 [100; 200]
Dialysate flow (ml/h)	2000 [2000; 2600]
Substitute flow rate (ml/h)	2000 [2000; 2375]
Ultrafiltration flow rate (ml/h)	100 [50; 100]
Dialysate dosis (ml/kg/h)	25.0 [18.0; 37.5]
Urine output during treatment	0 [0; 20]
Laboratory parameters before initiation of Cytosorb®
Myoglobin (ng/ml)	56,894 [11,544; 102,737]
CK (U/l)	14,822 [2565; 27,090]
Creatinine (mg/dl)	1.8 [1.5; 2.7]
Urea (mg/dl)	76 [51; 100]
Lactate (mmol/l)	2.5 [1.8; 5.4]
Bilirubin (mg/dl)	3.2 [1.8; 9.8]
LDH (U/l)	1153 [468; 2202]
Interleukin-6 (pg/ml)	226 [51; 1593]
CRP (mg/dl)	10.6 [5.5; 17]

Note: BMI: body mass index, ICU: intensive care unit, SAPS II: Simplified Acute Physiology Score, CK: creatine kinase, CVVHD(F): continuous veno-venous hemodialysis / hemodiafiltration, LDH: lactate dehydrogenase, CRP: C-reactive protein