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. 2024 Jun 21;10:294. doi: 10.1038/s41420-023-01764-9

Fig. 4. GSDMD overexpression and knockdown in endothelial cells do not affect endothelial function.

Fig. 4

A Western blot of GSDMD expression level of HUVECs transfected with plasmid DNA (GSDMD-OV) and siRNA (GSDMD-KD). B, C Relative cell proliferation rate of GSDMD-OV and GSDMD-KD HUVECs for 24 h. D, E Representative images and quantification of wound closure of GSDMD-OV and F, G GSDMD-KD HUVECs for 24 h. The value of relative wound closure was measured by ImageJ. Scale bar = 50 μm. n = 3 for each group; ns represents p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, #p < 0.0001.