Fig. 3.

Intervention time-series analysis to measure the impact of Xpert implementation. This analysis provides a comparative view of the real-world outcomes observed after Xpert implementation (illustrated by the black lines) versus the predicted observations in a scenario without its implementation (represented by the blue lines). The intervention year was chosen through a comprehensive anomaly detection analysis, which identified significant level-shifts in each time-series. Prediction intervals are presented at two confidence levels: 80% and 95%. These intervals are visually differentiated by two distinct shades of blue, with the lighter shade representing the broader 95% interval. Using this approach, we assessed the number of TB cases reported (A), DS tests (B), Mtb culture tests performed (C), DR-TB cases reported (D), smear microscopy (E), and cases of DS-TB notified (F). Abbreviations: TB, Tuberculosis; DR-TB, Drug-resistant tuberculosis; DS-TB, Drug-susceptible tuberculosis; MTB, Mycobacterium tuberculosis.