TABLE 1.
Susceptibility of cell lines to different strains of MV
| Cell line | Species | Derivation | CPE by MV strain
|
|
|---|---|---|---|---|
| Edmonston | KA | |||
| B95a | Marmoset | Adherent subline of B95-8 | + | + |
| Vero | Monkey | Kidney | + | − |
| HeLa | Human | Cervical carcinoma | + | − |
| BHK-21 | Hamster | Kidney | −a | − |
| RK13 | Rabbit | Kidney | −a | − |
| CHO | Hamster | Ovary | − | − |
| CHO/pME18S | Hamster | CHO transfected with the expression vector | − | − |
| CHO/CD46 | Hamster | CHO transfected with human CD46 cDNA | + | − |
| L | Mouse | Connective tissue | −a | − |
| L.Neo | Mouse | L transfected with the expression vector | −a | − |
| L.CD46.1 | Mouse | L transfected with human CD46 cDNA | + | − |
| B95-8 | Marmoset | EBV-transformed B cell | + | + |
| Raji | Human | Burkitt's lymphoma (EBV positive) | + | + |
| Daudi | Human | Burkitt's lymphoma (EBV positive) | +b | − |
| Ramos | Human | Burkitt's lymphoma (EBV negative) | + | + |
| BJAB | Human | Burkitt's lymphoma (EBV negative) | + | − |
| BJAB-B95-8 | Human | EBV-infected line of BJAB | + | + |
| MT-2 | Human | HTLV-1-transformed cord blood cell | + | + |
| C91/PL | Human | HTLV-1-transformed cord blood cell | + | + |
| Jurkat | Human | T-cell leukemia | + | − |
| MOLT-4 | Human | T-cell leukemia | + | − |
| THP-1 | Human | Monocytic leukemia | + | − |
| U-937 | Human | Histiocytic lymphoma (macrophage) | + | − |
| HL-60 | Human | Promyelocytic leukemia | + | − |
| RMA | Mouse | T-cell lymphoma | − | − |
| EL4 | Mouse | T-cell lymphoma | − | − |
a
The Edmonston strain of MV caused a few giant cells on these nonprimate cell lines when infected at a high MOI (>10).
b
CPE caused by the Edmonston strain of MV was weaker on Daudi than CPE on other human cell lines in suspension.