Figure 3. Post Hoc Subgroup Analysis of Hemoglobin A_1c (HbA_1c) Concentrations at Week 16 by Intention-to-Treat Analysis.

Patients were randomized to receive intermittent fasting plan consisting of 2 nonconsecutive fasting days and 5 days of habitual intake per week and meal replacement diet (5:2 MR) (n = 135), metformin (n = 134), or empagliflozin (n = 136). BMI indicates body mass index (calculated as weight in kilograms divided by height in meters squared); and LSM, least-squares mean.