2. Interventions.
Study | Surgical treatment | Medical treatment | Comparison description |
Alobid 2005 | GA endoscopic sinus surgery (variable extent) then topical budesonide 400 µg bd for 1 year | Oral prednisolone for 14 days (30 mg od 4 days then reduced by 5 mg every 2 days) then topical budesonide 400 µg bd for 1 year | Endoscopic sinus surgery versus systemic steroids |
Lildholdt 1988 | LA polypectomy then topical beclomethasone dipropionate 100 µg bd for 1 year | 14 mg im betamethasone then topical beclomethasone dipropionate 100 µg bd for 1 year | Polypectomy versus systemic steroids |
Lildholdt 1997 | LA snare polypectomy then topical budesonide 400 µg or 800 µg od for 11 months | 14mg im betamethasone then topical budesonide 400 µg or 800 µg od for 11 months | Polypectomy versus systemic steroids |
Ragab 2004 | GA endoscopic sinus surgery (variable extent) then antibiotics for 2 weeks plus topical fluticasone propionate spray 100 µg bd for 12 weeks, then "tailored treatment" | Antibiotics plus topical fluticasone propionate drops 400 µg bd for 12 weeks, then "tailored treatment" | Endoscopic sinus surgery plus topical steroid versus antibiotics plus high‐dose topical steroid |
bd: twice daily GA: general anaesthesia im: intramuscular LA: local anaesthesia od: once daily