Fig. 7.

Schematic illustration of the importance of c-MET in immune cells during BLM-induced PF progression. Lung injury is induced by BLM leading to uncontrolled inflammatory recruitment, followed by excessive deposition of extracellular matrix proteins, as collagen. Absence of c-Met in immune cells resulted in anticipated inflammatory recruitment, attenuated proinflammatory environment, leading to higher epithelial repair, which later culminates in lower collagen deposition and prevents fibrosis