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. 2024 Mar 4;326(4):C1248–C1261. doi: 10.1152/ajpcell.00726.2023

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Copyright © 2024 The Authors.

Licensed under Creative Commons Attribution CC-BY 4.0. Published by the American Physiological Society.

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Figure 2. — Depot-specific adipose-derived stem cell (ADSC) subpopulations. UMAPs and stacked bar-plots showing the repartition of the ADSCs subpopulations according to the adipose tissue depot [abdominal (ABD) vs. gluteofemoral (GF)] (A and B). Heatmap representation of the top five most upregulated genes (higher fold change) in each cluster of cells (C). Dotplot showing the significant pathways that are upregulated in each cluster; selected pathways with FDR < 0.05 are represented (D). Venn diagrams showing the common and unique genes differentially expressed in mesenchymal stem cell (MSC)-1, MSC-2, and MSC-3 and belonging to “Myc Target V1,” Fatty acid metabolism,” “Adipogenesis,” and cholesterol metabolism” pathways (E). SMC, smooth muscle cell.