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Case
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Treatment given (1 mg/kg of prednisolone)
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Treatment response
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Timing of the onset of a new lesion and fever
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Split-dose timing
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Response to a split dose
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Serum cortisol (5-25 mcg/dL) during follow-up
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|
1
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50 mg of prednisolone with thalidomide
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The patient was still getting new lesions even after one week
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1 AM
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8 AM: 30 mg; 8 PM: 20 mg
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After 48 hours, there were no new lesions
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14 mcg/dL
|
|
2
|
50 mg of prednisolone with thalidomide
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New pustules with high-grade fever even after five days of prednisolone
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10 PM
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8 AM: 30 mg; 8 PM: 20 mg
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No new lesions after 24 hours; patient afebrile after two days
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18 mcg/dL
|
|
3
|
60 mg of prednisolone with thalidomide for one month
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Still getting ENL lesions intermittently
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7 to 8 PM
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7 AM: 30 mg; 7 PM: 30 mg
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No new lesions after one week
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12 mcg/dL
|
|
4
|
65 mg of prednisolone with thalidomide for three weeks
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Still getting nodules with fever and joint pain
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4 AM
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8 AM: 35 mg; 8 PM: 30 mg
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No new lesions after three days
|
15 mcg/dL
|
|
5
|
40 mg of prednisolone with thalidomide for four weeks
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Still getting nodules with ulcers along with fever, joint pain, and redness of the eyes
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10 to 11 PM
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8 AM: 20 mg; 8 PM: 20 mg
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No new lesions after a week
|
20 mcg/dL
|
|
6
|
50 mg of prednisolone with thalidomide for four weeks
|
New nodules at a two- to three-day interval
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5 to 6 AM
|
8 AM: 30 mg; 8 PM: 20 mg
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No new lesions after seven to 10 days
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10 mcg/dL
|
|
7
|
60 mg of prednisolone with thalidomide for four months
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New nodules after four to five days
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5 to 6 PM
|
8 AM: 40 mg; 8 PM: 20 mg
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No new lesions after 48 hours
|
19 mcg/dL
|
|
8
|
50 mg of prednisolone with thalidomide for one month
|
New nodules after one to two days
|
9 to 10 PM
|
8 AM: 30 mg; 8 PM: 20 mg
|
No new lesions after three days
|
12 mcg/dL
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