Table 1.
Publications reporting 5-year relative survival (%) of Merkel cell carcinoma by sex in chronological order of publication year
| Publication | Population and time period | Comment | 5-year relative survival %) | Multivariable-adjusted hazard ratio (95% CI) | |
|---|---|---|---|---|---|
| Men | Women | ||||
| Agelli and Clegg [4] | U.S., SEER, 1973–1999 | No sex stratification of relative survival | 62 | 0.71 (0.59–0.87) | |
| Reichgelt et al. [123] | Netherlands, 1993–2007 | 55 | 67 | 0.71 (0.58–0.86) | |
| Kukko et al. [5] | Finland, 1983–2004 | No additional multivariable modelling | 36 (20–54) | 69 (56–82) | |
| Youlden et al. [7] | Queensland, 1993–2010 | 38 (30–47) | 48 (365–60) | 0.77 (0.5–1.16) | |
| Rubio-Casadevall et al. [124] | Girona (Spain), 1994–2002 | No sex stratification (26 cases only) | 44 (26–74) | ||
| Eisemann et al. [14]a | Germany, 2007–2011 | No additional multivariable modelling | 58 (51–65) | 84 (79–88) | |
| Lee et al. [64] | New Zealand, 2000–2015 | 43 (36–51) | 47 (39–55) | 0.86 (0.71–1.04) | |
| Uitentuis et al. [125] | Netherlands, 1993–2015 |
62 (years 1993–2000) 65 (years 2011–2016) |
0.70 (0.63–0.79) | ||
PubMed search [“relative survival” AND Merkel cell carcinoma], May 4, 2023; all survival estimates including 95% confidence limits were rounded to zero decimal places; Multivariable, stage-adjusted hazard ratios for death from any cause for the sex effect (reference group: men)
aThe authors themselves critically note that the relative survival probabilities may have been overestimated due to an under registration of deaths