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. Author manuscript; available in PMC: 2024 Aug 1.
Published in final edited form as: Stem Cell Res. 2024 May 29;78:103457. doi: 10.1016/j.scr.2024.103457
Unique stem cell line identifier NCHi015-A
Alternative name(s) of stem cell line NCH178 (NCHi015-A)
Institution Center for Cardiovascular Research, Abigail
Wexner Research Institute, Nationwide
Children’s Hospital, Columbus, OH, USA
Contact information of distributor Mingtao Zhao, PhD
Mingtao.Zhao@nationwidechildrens.org
Type of cell line iPSC
Origin Human
Additional origin info required for human ESC or iPSC Age: 1 year
Sex: Male
Race: Caucasian, Non-Hispanic
Cell Source Peripheral Blood Mononuclear Cells (PBMC)
Clonality Clonal
Method of reprogramming Sendai Virus vectors
Genetic Modification Yes
Type of Genetic Modification Congenital
Evidence of the reprogramming transgene loss (including genomic copy if applicable) RT-PCR KOS Transgene Negative (Supplementary Fig. 1C)
Associated disease Truncus Arteriosus Type I
Gene/locus KMT2D: c.2868G > C (12q13.12); NOTCH1: c.1099 + 1G > T (9q34.3)
Date archived/stock date 05/18/2023
Cell line repository/bank NCHi015-A (NCH178) is deposited in the iPSC repository of pediatric cardiovascular disease in the Center for Cardiovascular Research at the Abigail Wexner Research Institute at Nationwide Children’s Hospital in Columbus, OH, USA.https://hpscreg.eu/cell-line/NCHi015-A
Ethical approval Generation of this iPSC line was under an approved Institutional Review Board (IRB) protocol STUDY00001788 “iPSC Repository of Pediatric Cardiovascular Disease” at Nationwide Children’s Hospital.