| Unique stem cell line identifier | NCHi015-A |
| Alternative name(s) of stem cell line | NCH178 (NCHi015-A) |
| Institution | Center for Cardiovascular Research, Abigail Wexner Research Institute, Nationwide Children’s Hospital, Columbus, OH, USA |
| Contact information of distributor | Mingtao Zhao, PhD Mingtao.Zhao@nationwidechildrens.org |
| Type of cell line | iPSC |
| Origin | Human |
| Additional origin info required for human ESC or iPSC | Age: 1 year Sex: Male Race: Caucasian, Non-Hispanic |
| Cell Source | Peripheral Blood Mononuclear Cells (PBMC) |
| Clonality | Clonal |
| Method of reprogramming | Sendai Virus vectors |
| Genetic Modification | Yes |
| Type of Genetic Modification | Congenital |
| Evidence of the reprogramming transgene loss (including genomic copy if applicable) | RT-PCR KOS Transgene Negative (Supplementary Fig. 1C) |
| Associated disease | Truncus Arteriosus Type I |
| Gene/locus | KMT2D: c.2868G > C (12q13.12); NOTCH1: c.1099 + 1G > T (9q34.3) |
| Date archived/stock date | 05/18/2023 |
| Cell line repository/bank | NCHi015-A (NCH178) is deposited in the iPSC repository of pediatric cardiovascular disease in the Center for Cardiovascular Research at the Abigail Wexner Research Institute at Nationwide Children’s Hospital in Columbus, OH, USA.https://hpscreg.eu/cell-line/NCHi015-A |
| Ethical approval | Generation of this iPSC line was under an approved Institutional Review Board (IRB) protocol STUDY00001788 “iPSC Repository of Pediatric Cardiovascular Disease” at Nationwide Children’s Hospital. |