Table 1.
Demographic and disease information by ethnicity
| Overall N = 273 | Hispanic N = 189 | Non-Hispanic N = 84 | p-value1 | |
|---|---|---|---|---|
|
| ||||
| Age (median), years (IQR) | 6.5 (3.4, 12.5) | 7.4 (3.5, 13.2) | 5.2 (3.1, 9.6) | 0.018 |
|
| ||||
| Male, n (%) | 149 (54.6) | 108 (57.1) | 41 (48.8) | 0.2 |
|
| ||||
| Down syndrome, n (%) | 14 (5.1) | 10 (5.3) | 4 (4.8) | 0.9 |
|
| ||||
| WBC (median), K/µL (IQR) | 7.7 (3.1, 32.1) | 9.0 (3.1, 47.5) | 6.9 (3.0, 15.7) | 0.2 |
|
| ||||
| Subtype, n (%) | ||||
| Favorable | 101 (37.0) | 61 (32.3) | 40 (47.6) | 0.056 |
| Neutral | 78 (28.6) | 58 (30.7) | 20 (23.8) | |
| Unfavorable | 94 (34.3) | 70 (37.0) | 24 (28.6) | |
|
| ||||
| CNS2 or CNS3, n (%) 2 | 67 (24.7) | 56 (29.9) | 11 (13.1) | 0.004 |
|
| ||||
| NCI high risk, n (%) | 130 (47.6) | 100 (52.9) | 30 (35.7) | 0.009 |
|
| ||||
| EOI MRD+, n (%) 2 | 66 (24.4) | 50 (26.7) | 16 (19.0) | 0.2 |
1
Wilcoxon rank-sum test, Fisher’s exact test
2
N=271 (Hispanic: 187, Non-Hispanic: 84); IQR, interquartile range; WBC, white blood cell count; BM, bone marrow; CNS2, central nervous system 2 status at diagnosis; NCI high risk, National Cancer Institute risk score of 2 or 3; EOI, end of Induction; MRD, minimal/measurable residual disease.