Table 3.

The Graphene Oxide and Their Composite to Microenvironment in Cell Culture or Organoid Culture

Materials	Cell Line/ Primary Cell In Vitro	Applications	Cell Characteristics	Ref.
PANI–GO	SH-SY5Y, cortical neuronal cell	Tissue engineering and regeneration	Neurospheres formation.	[59]
CMCs-GelMa-GO-PLGA	HUVECs	Tissue engineering and regeneration	Tubule-like blood vessel network formation.	[60]
Ce-GO	HUVECs, HMSCs	Tissue engineering and regeneration	Spheroid formation.	[61]
EU/GL/TiO2	mESCs	Tissue engineering and regeneration	Embryoid bodies formation and colonies ESCs structures.	[62]
CH-GO	SH-SY5Y	Tissue engineering and regeneration	Cell phenotype like epithelial, cell growth is spread and elongated uniformly on the cell surface.	[64]
rGOM	ARPE-19, HCE-T	Tissue engineering and regeneration	Cells formed “polygonal”.	[65]
rGO-PCL	ADSCs	Tissue engineering and regeneration	Elongated spindle – like morphology.	[66]
adECM-PDA-rGO	NE-4C neuronal cell line	Tissue engineering and regeneration	Neuron like structures formation.	[67]
rGO-Mxene	MSU-1.1, HeLa, SH-SY5Y	Tissue engineering and regeneration	Maintaining cell phenotype.	[68]
SPI-SH-GA@PGO	HUVECs	Skin therapy	Tubule-like blood vessel network formation.	[70]
GO/rGO	MSCs	Therapeutic agents	Cells elongated with large nucleus (type of MSCs) and maintaining cell phenotype.	[84]
PEG-GO	MDA-MB-231, MDA-MB-436, MCF-10A	Cancer Therapy	Breast cancer cells metastated.	[86]