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. 2024 Jun 10;15:1397072. doi: 10.3389/fimmu.2024.1397072

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Copyright © 2024 Heine, Alessandrini, Grosch, Graß, Heldner, Schnautz, Grosch, Buters, Slusarenko, Krappmann, Fallarino, Ohnmacht, Schmidt-Weber and Blank

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Short-term effects of 10-Cl-BBQ treatment and AIT on BALF cell counts and cytokine levels. (A) Total and differential BALF cell counts and (B) cytokine levels in the BALF measured at the end (day 43) of the experiment (n = 5 – 8). Gaussian and non-Gaussian distributed results were analyzed by 1-way ANOVA with Tukey’s test or Kruskal-Wallis test with Dunn’s test, respectively. The bar charts show the mean with standard deviation. p-values of ≤.05, ≤.01, ≤.001, and ≤.0001 are shown as *, **, ***, and ****, respectively. AIT, allergen-specific immunotherapy; BQ, 10-Cl-BBQ; BALF, bronchoalveolar lavage fluid; CD, cluster of differentiation; IL, interleukin.