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List of TLRs, their location and ligands.
| TLRs | Ligands | Expression |
|---|---|---|
| TLR2 TLR3 TLR4 TLR5 TLR7 TLR8 TLR9 |
Triacyl lipopeptide (24), peptidoglycan, lipopeptide, lipoprotein, zymosan (25), HMGB1 (26), HSP60 (27), HSP70 (28), hyaluronan (29) dsRNA (10), mRNA (30) LPS (5), HMGB1, HSP60, HSP70, hyaluronan flagellin (11) ssRNA (31), siRNA (32) ssRNA (31), siRNA (32) unmethylated CpG (15), HMGB1 (33), DNA (34) |
Plasma membrane Endosome Plasma membrane Plasma membrane Endosome Endosome Endosome |
