Comparison 4. High‐dose ACTH versus low‐dose ACTH.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Cessation of spasms	2	85	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.06 [0.44, 2.56]
2 Relapse rates ‐ number of patients who remain spasm free	2	85	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.79 [0.33, 1.88]
3 Resolution of hypsarrhythmia	2	52	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.94 [0.60, 6.20]