Table 2.
Pathogens detected in AE-COPD patients with and without pneumonia
| Pathogens | Multiplex real-time PCR | Bacterial culture | Total | ||||
|---|---|---|---|---|---|---|---|
| AE-COPD with pneumonia (N = 92) |
AE-COPD only (N = 46) |
AE-COPD with pneumonia (N = 92) |
AE-COPD only (N = 46) |
AE-COPD with pneumonia (N = 92) |
AE-COPD only (N = 46) |
p | |
| Identified results | |||||||
| Pathogen detected | 73 (79.35) | 31 (67.39) | 50 (54.35) | 30 (65.22) | 85 (92.39) | 40 (86.96) | 0.30 |
| No pathogen detected | 19 (20.65) | 15 (32.61) | 42 (45.65) | 16 (34.78) | 7 (7.61) | 6 (13.04) | |
| Number of pathogen detected | |||||||
| Single | 47 (64.38) | 21 (67.74) | 50 (100) | 30 (100) | 59 (69.41) | 30 (75.00) | 0.41 |
| Mixed | 26 (35.62) | 10 (32.26) | 0 (0) | 0 (0) | 26 (30.59) | 10 (25.00) | |
| Pathogen detected subgroups | |||||||
| Single Gram-negative bacteria | 42 (57.53) | 17 (54.84) | 40 (80.00) | 24 (80.00) | 45 (52.94) | 20 (50.00) | 0.31 |
| Single Gram-positive bacteria | 3 (4.11) | 3 (9.68) | 10 (20.00) | 6 (20.00) | 12 (14.12) | 9 (22.50) | |
| Virus only | 2 (2.74) | 1 (3.22) | ND | ND | 2 (2.35) | 1 (2.50) | |
| Mixed bacteria | 23 (31.51) | 8 (25.81) | 0 (0) | 0 (0) | 23 (27.06) | 8 (20.00) | |
| Mixed bacteria and virus | 3 (4.11) | 2 (6.45) | ND | ND | 3 (3.53) | 2 (5.00) | |
The values are given as numbers (%)
AE-COPD, acute exacerbation of chronic obstructive pulmonary disease; ND, not determined