Wang 2009a.
| Methods | Study design: randomised controlled trial. Method of randomisation: no description. Concealment of allocation: no description. Exclusions post randomisation: none. Losses to follow‐up: none. Intention‐to‐treat analysis: not mentioned. | |
| Participants | Participants were those who underwent PCI successfully (residual stenosis < 20%), aging from 35 to 74. Tong‐xin‐luo group: 40 participants (male/female: 28/12; age: 54.2 ± 10.2 years). Control group: 40 participants (male/female: 26/14; age: 52.5 ± 11 years). |
|
| Interventions | Control group: Conventional treatment (low molecular weight heparin 6000 IU subcutaneous injection bid for 5 days; aspirin 100 mg qd, clopidogrel 75 mg qd). Tong‐xin‐luo group: conventional treatment plus Tong‐xin‐luo capsules (3 capsules, tid; 0.38 g/capsule). Duration of intervention: 6 months. Co‐intervention: none. |
|
| Outcomes | Occurrence of myocardial infarction and angina. | |
| Notes | ||
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Randomised, but detailed information on the randomisation method was not provided. |
| Allocation concealment (selection bias) | Unclear risk | No description about the allocation procedure. |
| Blinding of participants and personnel (performance bias) All outcomes | High risk | No description about blinding. No placebo. |
| Blinding of outcome assessment (detection bias) All outcomes | High risk | No description about blinding. No placebo. |
| Incomplete outcome data (attrition bias) Angiographic restenosis | Unclear risk | The outcome was not reported. |
| Incomplete outcome data (attrition bias) Outcomes other than angiographic restenosis | Low risk | There was no loss to follow‐up. |
| Selective reporting (reporting bias) | Unclear risk | The study protocol is not available. |
| Other bias | Low risk | Baseline information showed no statistical differences in sex, age, smoking, comorbidities, length of lesion and distributions of coronary pathological changes between the two groups (P > 0.05). The study appeared to be free of other sources of bias. |