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. 2015 May 21;2015(5):CD010237. doi: 10.1002/14651858.CD010237.pub2

Han 2012.

Trial name or title Tongxinluo Improve High on Clopidogrel Platelet Reactivityn Patients With Coronary Heart Disease
Methods Randomised double‐blind trial
Participants ACS (including unstable angina pectoris, non‐ST‐segment elevation myocardial infarction and ST‐elevation myocardial infarction; at least one coronary stent; age between18 and 75; high on‐treatment platelet reactivity defined as an ADP‐induced platelet aggregation (by VerifyNow, PRU ≥ 236) at 24 hours after clopidogrel loading (300 ‐ 600 mg) or 24 hours after PCI.
Interventions Tong‐xin‐luo
Outcomes Platelet aggregation rate;
Inflammation Marker (hsCRP, CD62P‐CD41);
 BT, FIB and aPTT;
 Major ischemic event (including MI, ischemic stroke and all‐cause mortality);
 Bleeding event;
 Adverse drug reaction and withdrawal rate;
 Angina recurrence;
 Traditional Chinese medicine angina symptoms scores;
 Intra‐stent thrombosis.
Starting date November 1, 2012
Contact information Yaling Han, MD Tel: +86‐24‐23922184 E‐mail: 13998847715@qq.com
Notes  

Abbreviations

ACS: acute coronary syndrome
 PRU: P2Y12 reactivity unit
 PCI: percutaneous coronary intervention
 aPTT: activated partial thromboplastin time
 MI: miocardial infarction