Figure 6. SLIRP downregulation enhances OC43 infection and attenuates ISG induction.

(A) Western blot analysis of SLIRP expression in A549 cells transduced with shSLIRP. (B, C) Analysis of viral mRNA expression (B) and ISG induction (C) after infecting SLIRP-deficient cells with OC43 at MOI = 1. N=3 and error bars denote s.e.m. All of the statistical significances were calculated using one-tail Student’s t-tests; * p ≤ 0.05, ** p ≤ 0.01, and *** p ≤ 0.001.