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[Preprint]. 2024 Jun 11:2024.06.11.598425. [Version 1] doi: 10.1101/2024.06.11.598425

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Fig. 6. — Periderm-specific ablation of Irf6 results in a comparable but mild form of the global Irf6 KO phenotype. Krt6ai-Cre⁺;Irf6^fl/fl and littermate control neonates were collected at P1. A. Lateral and caudal representation of neonates comparing control Krt6ai-Cre⁻;Irf6^fl/fl with Krt6ai-Cre⁺;Irf6^fl/fl cKO. B. Krt6ai-Cre⁻;Irf6^fl/fl exhibit normal skin and digits; however Krt6ai-Cre⁺;Irf6^fl/fl reveal abnormal skin and fused digits phenotype. Scale: 500 μM. C. Hematoxylin and Eosin staining of coronal sections through vomeronasal and primary palate of neonates. Krt6ai-Cre⁻;Irf6^fl/fl mice show normal septum and palate. Krt6ai-Cre⁺;Irf6^fl/fl mice reveal abnormal septum and adhesions of the tongue.