Extended Data 3. Calcium activity changes in PACAPPBL→DR neurons do not respond as a general multi-modal aversive circuit.
a, Average calcium trace during “Conditioning” phase of the fear conditioning test. Blue shading indicates “Tone ON” periods and orange arrows indicate when the foot shock was given. n = 3 mice. b, Average calcium trace during the looming test with corresponding AUC analysis. Pink shading indicates the 2-s looming exposure. Repeated measure one-way ANOVA with Sidak’s multiple comparisons test, F (2, 6) = 240.127, P < 0.001. n = 4 mice. Data are presented as the mean ± SEM; see also Supplementary Table 3 for statistical details. **P<0.01.