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. Author manuscript; available in PMC: 2024 Jun 24.
Published in final edited form as: Nat Neurosci. 2024 Jan 4;27(1):90–101. doi: 10.1038/s41593-023-01504-3

Extended Data 4. Calcium activity changes in PACAPPBL→DR neurons during anxiogenic conditions.

Extended Data 4.

a, Schematic of the elevated platform test. b, Average calcium trace during elevated platform assessment, and corresponding area under curve (AUC) analysis. Paired two-sided t-test, P = 0.0017. n = 4 mice. c, Schematic of the elevated plus maze. d, Average calcium trace during the seconds immediately preceding and following open arm entry and exit, with corresponding AUC analysis. Paired two-sided t-test, P < 0.0001. n = 4 mice. e, Calcium traces from individual animals. Pink shading indicates when mice were in the open arm. n = 4 mice. Data are presented as the mean ± SEM; see also Supplementary Table 3 for statistical details. **P<0.01, ***P<0.001.