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. 2024 Jun 18;147(1):102. doi: 10.1007/s00401-024-02754-6

Table 3.

Clinical and demographic baseline data of follow-up patients

Age (years) Gender Baseline QMG Baseline MG-ADL Follow-up QMG Follow-up MG-ADL Baseline therapy Follow-up therapy Baseline ITIH3 (ng/ml) Follow-up ITIH3 (ng/ml) Follow-up time point (months) Steroids (mg/day) Responder
43 f 9 11 9 6 MMF AZA 1592.849 890.391 8 0 Yes
68 m 13 8 13 5 Naïve MTX 1203.973 832.151 4 5 Yes
54 m 10 25 4 8 Naïve ECU 561.49 950.29 6 5 Yes
28 f 16 24 12 16 Naïve EFG 1543.299 748.127 6 5 Yes
54 m 12 7 4 2 RTX ECU 684.299 291.227 8 0 Yes
62 f 22 30 12 16 Naïve ECU 1832.291 983.221 6 2.5 Yes
21 f 6 12 7 9 Naïve AZA 890.829 560.322 6 5 Yes
32 f 12 18 8 12 Naïve ECU 1993.289 482.991 6 0 Yes
68 m 20 19 2 3 AZA ECU 1693.289 493.392 6 0 Yes
36 f 10 12 7 6 Naïve EFG 1294.299 439.29 6 2.5 Yes
66 m 15 4 15 11 Naïve AZA 792.382 827.382 4 5 No
61 m 2 3 2 3 MMF AZA 178.299 114.293 4 7,5 no
73 m 10 4 10 3 MMF AZA 672.407 635.495 4 0 no
37 f 1 3 1 2 Naïve AZA 359.8676 325.841 4 0 no
31 f 13 11 13 12 Naïve RTX 625.291 389.211 6 10 no
66 m 2 5 6 5 AZA ECU 522.832 581.74 4 5 no
32 f 3 8 3 8 Naïve AZA 798.299 438.128 6 0 no

Individual clinical and demographic data of follow-up patients. MG patients were defined as treatment responders if they improved by ≥ 3 points on the MG-ADL scale. ITIH3 levels were measured in serum samples by ELISA. All patients were anti-AChR-Ab positive

AChR acetylcholine receptor, Ab antibody, AZA azathioprine, ECU eculizumab, EFG efgartigimod, f female, ITIH3 inter-alpha-trypsin inhibitor heavy chain H3, m male, MG-ADL myasthenia gravis activities of daily living, MMF mycophenolate-mofetil, MTX methotrexate, QMG quantitative myasthenia gravis, RTX rituximab