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. Author manuscript; available in PMC: 2024 Jun 24.
Published in final edited form as: World J Biol Psychiatry. 2021 Jun 3;22(9):722–731. doi: 10.1080/15622975.2021.1907711

Table 2.

Summary of results from our genome-wide association study of SCAN Suicide Severity (6.011) and SCAN Suicidality (SSU) scores.

Phenotype SNP Gene eQTLa CHR BP Z-score p Direction

6.011 rs9654143 STPG2 STPG2/RAP1GDS1 4 98,689,152 −5.054 4.33E − 07 –––
6.011 rs9647614 MCUR1 6 13,843,271 4.892 9.98E − 07 +++
6.011 rs61246028 LINC00400 13 43,756,955 4.703 2.57E − 06 +++
6.011 rs79099900 RASSF2 20 4,804,781 −4.692 2.71E − 06 –––
6.011 rs74961332 POFUT2 POFUT2 21 46,702,822 4.779 1.76E − 06 +–+
SSU rs9654143 STPG2 STPG2/RAP1GDS1 4 98,689,152 −5.054 4.33E − 07 +++
SSU rs9647614 6 13,843,271 4.892 9.98E – 07 –––
SSU rs61246028 LINC00400 13 43,756,955 4.703 2.57E − 06 +++
SSU rs77916371 PTPN21 14 88,969,691 −4.522 6.13E − 06 –––
SSU rs11071625 LOC107984782 15 61,967,903 −4.562 5.07E − 06 –––

Gene Name Gene ID Number of SNPs CHR N ZSTAT p NPERM

6.011 ACE 1636 61 17 3506 3.7384 9.26E − 05 1000
6.011 GFRA1 2674 666 10 3506 4.1658 1.55E − 05 1000
6.011 STPG2 285555 1887 4 3506 3.9027 4.76E − 05 1000
6.011 IQCA1 79781 373 2 3506 4.1165 1.92E − 05 1000
SSU GFRA1 2674 666 10 3506 3.9624 3.71E − 05 1000
SSU STPG2 285555 1887 4 3506 3.8058 7.07E − 05 1000
SSU DNASE2B 58511 92 1 3506 3.7905 7.52E − 05 1000

The upper panel shows the top five SNPs for each phenotype, and the bottom panel shows the top suggestive gene-based findings for these phenotypes.

a

According to GTEx portal.