Table 2.
Cox proportional-hazard regression analysis for Overall Survival in 219 patients with CRC
| Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| P-value | HR | 95.0% CI for Exp (B) | P-value | HR | 95.0% CI for Exp (B) | |||
| Lower | Upper | Lower | Upper | |||||
| Gender | 0.941 | 0.983 | 0.619 | 1.560 | ||||
| Age | 0.930 | 1.021 | 0.664 | 1.617 | ||||
| Tumor location | 0.324 | 1.010 | 0.636 | 1.605 | ||||
| Differentiation | 0.000 | 5.109 | 3.184 | 8.192 | 0.197 | 1.616 | 0.780 | 3.349 |
| Depth of invasion | 0.015 | 5.857 | 1.628 | 21.075 | 0.061 | 6.713 | 0.915 | 24.625 |
| T1 + T2 | ||||||||
| T3 + T4 | ||||||||
| Lymph node metastasis | 0.000 | 2.580 | 1.629 | 4.087 | 0.024 | 1.805 | 1.081 | 3.014 |
| N0 | ||||||||
| N+ | ||||||||
| Distant metastasis | 0.000 | 6.750 | 4.173 | 10.920 | 0.006 | 2.712 | 1.336 | 5.503 |
| TNM stage | 0.000 | 3.993 | 2.458 | 6.448 | ||||
| I + II | ||||||||
| III + IV | ||||||||
| CEA level | 0.045 | 1.602 | 1.011 | 2.537 | 0.888 | 1.038 | 0.619 | 1.742 |
| CA19-9 level | 0.101 | 1.554 | 0.917 | 2.632 | ||||
| Vessel or nerve invasion | 0.000 | 5.940 | 3.694 | 9.551 | 0.028 | 1.989 | 1.077 | 3.670 |
| Chemotherapy or not | 0.521 | 0.859 | 1.541 | 1.366 | 0.001 | 2.357 | 1.441 | 3.855 |
| MEX3A expression | 0.000 | 3.122 | 1.888 | 5.164 | 0.002 | 2.132 | 1.254 | 3.625 |
| Low | ||||||||
| High | ||||||||