Table 3.

Cox proportional-hazard regression analysis for Recurrence Free Survival in 219 patients with CRC

	Univariate analysis				Multivariate analysis
	P-value	HR	95.0% CI for Exp (B)		P-value	HR	95.0% CI for Exp (B)
			Lower	Upper			Lower	Upper
Gender	0.314	1.382	0.736	2.592
Age	0.726	0.893	0.476	1.677
Tumor location	0.295	0.708	0.372	1.351
Differentiation	0.009	2.540	1.263	5.108	0.216	1.672	0.740	3.776
Depth of invasion	0.051	7.248	0.995	52.795
T1 + T2
T3 + T4
Lymph node metastasis	0.020	2.140	1.130
N0
N+
TNM stage	0.017	2.240	1.133	4.064	0.736	1.147	0.516	2.550
I + II
III + IV
CEA level	0.043	1.913	1.019	3.591	0.049	1.912	1.002	3.647
CA19-9 level	0.626	1.228	0.538	2.804
Vessel or nerve invasion	0.000	4.279	1.957	9.353	0.023	2.597	1.142	5.904
Chemotherapy or not	0.236	1.463	0.780	2.747	0.941	1.026	0.513	2.055
MEX3A expression	0.001	3.252	1.644	6.431	0.002	3.021	1.142	5.904
Low
High