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. 2024 Jun 24;14:14572. doi: 10.1038/s41598-024-64925-5

Table 2.

Comparison of ophthalmic examination between subgroups.

Characteristics Mean ± SD Mean ± SD Mean ± SD
Female Male p-value Non-smokers smokers P-value No Hx of thyroidectomy Hx of thyroidectomy P-value
VA (logMAR)_pre 0.07 ± 0.12 0.05 ± 0.12 0.93 0.08 ± 0.14 0.01 ± 0.02 0.032 0.07 ± 0.13 0 ± 0 0.14
Exophthalmos_Pre 24 ± 3.8 26.5 ± 2 0.015 24.2 ± 3.5 27 ± 2.5 0.18 24.9 ± 3.6 24.7 ± 0.6 0.01
MRD1_Pre 6 ± 2.1 6.9 ± 3.6 0.034 6.1 ± 2 6.8 ± 4.2  < 0.001 6.4 ± 2.6 5.3 ± 3.5 0.75
MRD2_pre 6.6 ± 1.2 6.8 ± 1.8 0.361 6.2 ± 1 7.9 ± 1.6 0.31 6.7 ± 1.4 6.5 ± 1.3 0.82
IOP_pre 16.5 ± 3.5 17.6 ± 2.2 0.081 16.8 ± 3.1 17.3 ± 3.2 0.64 16.8 ± 3.2 17.7 ± 0.6  < 0.01
CAS_Pre 0.7 ± 0.92 1.36 ± 0.81 0.867 0.91 ± 0.95 1 ± 0.93 0.50 0.96 ± 0.92 0.67 ± 1.15 0.44
Vessel density-nasal superficial 0.37 ± 0.07 0.42 ± 0.08 0.64 0.38 ± 0.05 0.41 ± 0.12  < 0.001 0.38 ± 0.07 0.41 ± 0.11 0.44
Vessel density-nasal deep 0.31 ± 0.07 0.37 ± 0.09 0,70 0.32 ± 0.06 0.37 ± 0.12 0.06 0.34 ± 0.07 0.29 ± 0.16 0.01
Vessel density-temporal superficial 0.4 ± 0.08 0.41 ± 0.07 0.90 0.4 ± 0.08 0.4 ± 0.08 0.52 0.4 ± 0.08 0.4 ± 0.06 0.52
Vessel density-temporal deep 0.34 ± 0.11 0.38 ± 0.1 0.85 0.35 ± 0.1 0.36 ± 0.14 0.03 0.36 ± 0.11 0.34 ± 0.11 0.56
Vessel length density-nasal superficial 0.18 ± 0.03 0.21 ± 0.04 0.42 0.19 ± 0.02 0.19 ± 0.06  < 0.001 0.19 ± 0.03 0.21 ± 0.07 0.04
Vessel length density-nasal deep 0.16 ± 0.03 0.2 ± 0.05 0.13 0.17 ± 0.03 0.19 ± 0.07 0.01 0.18 ± 0.03 0.16 ± 0.11  < 0.001
Vessel length density-temporal superficial 0.2 ± 0.03 0.21 ± 0.03 0.83 0.2 ± 0.03 0.21 ± 0.04 0.31 0.2 ± 0.03 0.21 ± 0.03 0.83
Vessel length density-temporal deep 0.19 ± 0.05 0.2 ± 0.05 0.63 0.2 ± 0.04 0.19 ± 0.07 0.04 0.2 ± 0.05 0.2 ± 0.04 0.60
Vessel diameter index-nasal superficial 2.08 ± 0.17 2.01 ± 0.12 0.45 2.05 ± 0.17 2.09 ± 0.14 0.68 2.06 ± 0.16 2.01 ± 0.12 0.55
Vessel diameter index-nasal deep 1.93 ± 0.14 1.9 ± 0.13 0.87 1.92 ± 0.14 1.93 ± 0.14 0.70 1.93 ± 0.13 1.88 ± 0.18 0.59
Vessel diameter index-temporal superficial 2 ± 0.17 1.93 ± 0.14 0.53 1.99 ± 0.17 1.95 ± 0.15 0.92 1.98 ± 0.16 1.94 ± 0.19 0.65
Vessel diameter index-temporal deep 1.84 ± 0.21 1.87 ± 0.17 0.62 1.85 ± 0.19 1.84 ± 0.22 0.84 1.86 ± 0.19 1.72 ± 0.2 0.97

CI confidence interval, SD standard deviation, CAS clinical activity score, Log-MAR logarithm of the minimum angle of resolution, IOP intraocular pressure, MRD1 margin-reflex diameter 1, MRD2 margin reflex diameter 2, Hx history.