FIG. 2.

P1-HIV line suppression of viral replication in autologous CD4⁺ T cells. (A) CD4⁺ T lymphocytes were acutely infected with the HIV-1 R5 strain YU2b. (B) CD4⁺ T cells were infected with the nef frameshift mutant YU2bΔnef. Infected cells were either cultured alone (■) or cocultured with antigen-stimulated P1-HIV line at CD8⁺/CD4⁺ ratios of 4/1 (⧫) or 1/1 (○). Results are expressed as the RT activity (cpm)/50 μl of culture supernatant.