Table 1.

My-Medula patient and professional profile modules, components, and clinical use.

Patient Modules	Components and clinical use
Treatment	Drug catalog synchronized with the Spanish National Formulary Medication list includes active treatment list and inactive drugs New medication list included by patient or caregiver. Pharmacist validates the treatment, checking for interactions All medication included in the active treatment list generates a visual and sonorous small alarm to help the patient remember taking their medication. Non pharmacologic treatments can also be included
Records	Vital signs (i.e., blood pressure, heart-rate, temperature, pain), biomeasurements (i.e., weight, height, blood glucose), dietary intake, exercise data Health questionnaires: i.e., medication adherence (ARMSe), anxiety and depression (HADS) Symptoms or adverse effects generate an alert to clinicians. A color code (red-orange-green) of the alert helps to prioritize intervention
Communication	A real-time bidirectional chat between patient and healthcare professional allows the attachment of images, files and audio recordings.
Agenda	A text alert can be triggered on the patient’s cell phone for drug intake alert and test appointment reminders.
Information	Information on healthy lifestyles (multimedia files, links to videos), on treatment and useful information about the team or the health center.
Help	A help center service to solve both technical and functional problems Clinical contact data The legal requirements accepted at first use are always available for consultation.
Healthcare Modules	Component and clinical use
Patient Reports	On the main page there is a list of active patients with colored traffic lights and registration alerts to help the clinicians prioritize their intervention. They can review and track: - New treatments introduced pending pharmacist validation - Vital signs - Symptoms and adverse events - Completion of questionnaires - Pending messages - Patient adherence - Patient inactivity (by filtering by the last activity date) All patient reported experience measures (PREMs) and patient reported outcomes measures (PROMs) recorded by patients can be downloaded, and filtered by date in Excel format.
Treatment Prescription	Pharmacological treatment is usually prescribed by pharmacist, patient or caregiver from a drop-down list of drugs updated from the Spanish National Formulary. Pharmacist validates the treatment, that has to be similar to computer order prescription. Tailored recommendations can be added

ARMSe, Adherence to Refill and Medication Scale; HADS, Hospital Anxiety and Depression Scale. Adapted from Redondo S, et al. (16).