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. 2024 Jun 11;15:1382861. doi: 10.3389/fendo.2024.1382861

Table 3.

Interaction analysis of the rs9838094 polymorphism with the covariate natal sex.

Interaction analysis with covariate natal sex
rs9838094 sex cross-classification interaction (n=187, crude analysis)
Females Males
Genotypes Cis group Trans group OR (95% CI) P-value Cis group Trans group OR (95% CI) P-value
G/G 30 37 Reference 1.00 24 36 1.22 (0.60–2.46) 0.592
T/G 18 10 0.45 (0.18–1.12) 0.086 16 10 0.51 (0.20–1.28) 0.155
T/T 2 0 0.00 4 0 0.00
Natal sex within rs9838094 (n=187, crude analysis)
Genotypes Natal sex Cis group Trans group OR (95% CI) P-value
G/G Females 30 37 Reference 1.00
Males 24 36 1.22 (0.60–2.46) 0.592
T/G Females 18 10 Reference 1.00
Males 16 10 1.12 (0.37–3.40) 0.851
T/T Females 2 0 Reference 1.00
Males 4 0 1.00
Test for interaction in the trend: 0.76
rs9838094 within natal sex (n=187, crude analysis)
Natal sex Genotypes Cis group Trans group OR (95% CI) P-value
Females G/G 30 37 Reference 1.00
T/G 18 10 0.45 (0.18–1.12) 0.086
T/T 2 0 0.00
Males G/G 24 36 Reference 1.00
T/G 16 10 0.42 (0.16–1.07) 0.073
T/T 4 0 0.00
Test for interaction in the trend: 0.99