Fig. 4.
Volume of distribution during saline and levodopa infusion in aromatic l-amino acid decarboxylase-rich regions. We compared volume of distribution (Vd) between saline infusion (OFF) and levodopa infusion (ON) conditions in Parkinson’s disease patients with or without levodopa-induced dyskinesia (LID). We detected no significant Vd changes in the aromatic l-amino acid decarboxylase (AADC)-rich regions-of-interest as well as ROIs devoid of AADC (a) or the volumes-of-interest of flow-metabolism dissociation (b). NLID non-LID