Table 1.
Study details for individual LID subjects
| Subject | Age (years) | Sex | Weight (Kg) | Disease duration | H&Y | LEDD (mg/Kg/day) | LEDD (mg/Kg/day) | LD infused (mg/Kg/h) | UPDRS OFF | UPDRS ON | UPDRS change(%) | UPDRS-IV |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 56 | M | 69.85 | 5 | 2 | 400 | 5.717 | 0.429 | 25 | 13 | 48.0 | 1 |
| 2 | 53 | F | 52.16 | 9 | 2 | 550 | 10.527 | 0.957 | 18 | 8 | 55.6 | 3 |
| 3 | 59 | M | 78.93 | 9 | 2 | 600 | 7.590 | 0.632 | 23 | 7 | 69.6 | 1 |
| 4 | 55 | M | 99.79 | 12 | 2 | 950 | 9.504 | 2.001 | 29 | 14 | 51.7 | 1 |
| 5 | 56 | M | 56.70 | 16 | 2 | 700 | 12.326 | 0.880 | 29 | 13 | 55.2 | 2 |
| 6 | 60 | M | 76.36 | 7 | 2 | 660 | 8.647 | 1.041 | 26 | 13 | 50.0 | 2 |
| 7 | 67 | F | 62.73 | 13 | 3 | 850 | 13.557 | 1.216 | 27 | 22 | 18.5 | 2 |
| 8 | 67 | F | 81.82 | 6 | 2 | 898 | 10.981 | 2.202 | 22 | 10 | 54.5 | 1 |
| Mean | 59.1 | 72.3 | 9.6 | 2.1 | 701.0 | 9.9 | 1.2 | 24.9 | 12.5 | 50.4 | 1.6 | |
| SD | 5.3 | 15.4 | 3.8 | 0.4 | 188.3 | 2.5 | 0.6 | 3.8 | 4.6 | 14.4 | 0.7 |
H&Y Hoehn and Yahr scale, LDD levodopa daily dose, LDD(w) weight-corrected levodopa daily dose, LEDD levodopa equivalent daily dose, LEDD(w) weight-corrected levodopa equivalent daily dose, LID Parkinson’s disease subjects with levodopa-induced dyskinesia, non-LID Parkinson’s disease subjects without LID, UPDRS Unified Parkinson’s Disease Rating Scale, UPDRS-IV dyskinesia severity