Table 2.
Correlations between LMO7 expression and staining intensity and clinicopathologic characteristics
| Variable | LMO7 expression | |||
|---|---|---|---|---|
| 0–50% n (%) |
51–100% n (%) |
P value | ||
| Sex | Male | 37 (47) | 42 (53) | 0.285b |
| Female | 11 (65) | 6 (35) | ||
| Stage TNM 8 | I | 1 (17) | 5 (83) | 0.177c |
| II | 28 (51) | 27 (49) | ||
| III | 14 (64) | 8 (36) | ||
| IV | 5 (38) | 8 (62) | ||
| Localization | Tonsil | 33 (53) | 29 (47) | 0.492c |
| Base of tongue | 10 (40) | 15 (60) | ||
| Other oropharyngeal | 5 (56) | 4 (44) | ||
| Differentiation grade | Low | 14 (37) | 24 (63) | 0.036c* |
| Moderate | 30 (62) | 18 (38) | ||
| High | 3 (33) | 6 (67) | ||
| NK | 1 | 0 | ||
| Smoking habit | Smoker | 31 (56) | 24 (44) | 0.097b |
| Nonsmoker | 13 (38) | 21 (62) | ||
| Unknown | 4 | 3 | ||
| Recurrence | Yes | 13 (65) | 7 (35) | 0.31b |
| No | 30 (45) | 36 (55) | ||
| Residual tumor | 5 (50) | 5 (50) | ||
| Vital status | Alive | 23 (40) | 34 (60) | 0.022b* |
| Dead | 25 (64) | 14 (36) | ||
| Cause of death | Cancer | 18 (62) | 11 (38) | 0.498b |
| Other | 6 (75) | 2 (25) | ||
| Unknown | 1 | 1 | ||
| LRIG1 expression | Absent | 0 | 1 (100) | 0.048c* |
| 1–25% | 0 | 0 | ||
| 26–50% | 1 (50) | 1 (50) | ||
| 51–75% | 5 (100) | 0 | ||
| 76–100% | 40 (47) | 45 (53) | ||
| NK | 2 | 1 | ||
| LRIG1 intensity | No | 0 | 1 (100) | 0.744c |
| Weak | 3 (75) | 1 (25) | ||
| Intermediate | 37 (49) | 38 (51) | ||
| Strong | 8 (53) | 7 (47) | ||
| NK | - | 1 | ||
| LMO7 intensity | No | 2 (100) | 0 | 0.05c |
| Weak | 12 (75) | 4 (25) | ||
| Intermediate | 21 (42) | 29 (58) | ||
| Strong | 4 (44) | 5 (56) | ||
| NK | 9 | 10 | ||
| CD44 expression | Absent | 7 (70) | 3 (30) | 0.275b |
| 1–25% | 13 (45) | 16 (55) | ||
| 26–50% | 4 (31) | 9 (69) | ||
| 51–75% | 12 (63) | 7 (37) | ||
| 76–100% | 11 (48) | 12 (52) | ||
| NK | 1 | 1 | ||
| CD44 intensity | No | 7 (70) | 3 (30) | 0.347b |
| Weak | 13 (45) | 16 (55) | ||
| Intermediate | 16 (43) | 21 (57) | ||
| Strong | 11 (61) | 7 (39) | ||
| NK | 1 | 1 | ||
| Ki67 expression | Mean | 33 (57) | 25 (43) | 0.093b |
| Mean | 14 (38) | 23 (62) | ||
| P53 expression | Wild-type | 37 (48) | 40 (52) | 0.442b |
| Mutated | 11 (58) | 8 (42) | ||
LMO7 LIM domain 7 protein, NK not known, LRIG leucine-rich repeats and immunoglobulin-like domain
aIndependent samples t-test
bChi2-test
cFisher’s exact test
* = P < 0.05