Table 3.
Correlations between HPV and LMO7 status and clinicopathologic characteristics
|
Variable N |
Frequency (%) 96 |
||||
|---|---|---|---|---|---|
| HPV + , LMO7 + |
HPV-, LMO7- |
HPV + , LMO7 - |
HPV -, LMO7 + |
P value | |
| Sex | |||||
| Male | 31 (39) | 9 (11.5) | 28 (35.5) | 11 (14) | 0.454a |
| Female | 5 (29) | 4 (24) | 7 (41) | 1 (6) | |
| Age (years) | |||||
| Range | 39–87 | 37–75 | 45–73 | 56–82 | 0.049b* |
| Mean | 58.6 | 61.9 | 57.9 | 66.5 | |
| Stage TNM 8 | |||||
| I | 4 (67) | 0 | 1 (16.5) | 1 (16.5) | < 0.001a* |
| II | 26 (47) | 3 (5.5) | 25 (45.5) | 1 (2) | |
| III | 6 (27) | 5 (23) | 9 (41) | 2 (9) | |
| IV | 0 | 5 (38.5) | 0 | 8 (61.5) | |
| Localization | |||||
| Tonsillar cancer | 26 (42) | 3 (5) | 30 (48) | 3 (5) | < 0.001a* |
| Base of tongue cancer | 9 (36) | 7 (28) | 3 (12) | 6 (24) | |
| Other oropharyngeal cancer | 1 (11) | 3 (33.5) | 2 (22) | 3 (33.5) | |
| Differentiation grade | |||||
| Low | 21 (55) | 1 (3) | 13 (34) | 3 (8) | 0.005a* |
| Moderate | 10 (21) | 9 (19) | 21 (44) | 8 (16) | |
| High | 5 (56) | 2 (22) | 1 (11) | 1 (11) | |
| NK | 1 | ||||
| Smoking habit | |||||
| Smoker | 15 (27) | 11 (20) | 20 (36.5) | 9 (16.5) | 0.029a* |
| Nonsmoker | 19 (56) | 2 (6) | 11 (32) | 2 (6) | |
| NK | 2 | 4 | |||
| Recurrence | |||||
| Yes | 5 (25) | 7 (35) | 6 (30) | 2 (10) | 0.017a* |
| No | 29 (44) | 4 (6) | 26 (39) | 7 (11) | |
| Residual tumor | 2 (20) | 2 (20) | 3 (30) | 3 (30) | |
| Vital status | |||||
| Alive | 30 (52.5) | 1 (2) | 22 (38.5) | 4 (7) | < 0.001c* |
| Dead | 6 (15) | 12 (31) | 13 (33) | 8 (21) | |