Table 3.
Association of sleep with the risk of incident liver cancer (N = 356,894)
| Sleep | Model 1 | Model 2 | Model 3 |
|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| Unhealthy sleep (sleep score: 0 ~ 3) | 1.35 (1.11, 1.64) | 1.43 (1.14, 1.79) | 1.46 (1.15, 1.85) |
| Independent sleep trait | |||
| Unfavorable sleep duration | 1.48 (1.21, 1.81) | 1.30 (1.03, 1.63) | 1.29 (1.01, 1.65) |
| Evening chronotype | 1.07 (0.83, 1.38) | 1.28 (0.95, 1.73) | 1.18 (0.85, 1.64) |
| Insomnia | 1.51 (1.23, 1.86) | 1.37 (1.08, 1.73) | 1.43 (1.11, 1.83) |
| Snoring | 0.85 (0.70, 1.04) | 1.24 (0.98, 1.56) | 1.30 (1.01, 1.67) |
| Excessive daytime sleepiness | 1.57 (0.95, 2.59) | 1.17 (0.67, 2.05) | 1.28 (0.73, 2.25) |
Model 1 was a crude model; Model 2 was adjusted for age, sex, ethnicity, BMI, smoking status, alcohol consumption, healthy diet, and physical activity; Model 3 was adjusted for age, sex, ethnicity, BMI, smoking status, alcohol consumption, healthy diet, physical activity, any treatment/medication taken, Townsend deprivation index, family history of cancer, and CRP
Abbreviations: HR hazard ratio, CI confidence interval