Table 8.
Variables | Total (n = 61) | Normal (n = 19) | Mild (n = 15) | Moderate (n = 19) | Severe (n = 8) | p-value |
---|---|---|---|---|---|---|
WMV | 32.9 (30.8, 34.6) | 34.5 (32.05, 35.1) | 34.2 (33.4, 34.8) | 31.5 (29.2, 33.45) | 29.15 (28.38, 30.35) | <0.001 |
GMV | 607.26 ± 29.72 | 607.94 ± 44.2 | 607.96 ± 16.14 | 606.55 ± 24.85 | 606.01 ± 20.87 | 0.998 |
CSF | 124.61 ± 22.52 | 114.48 ± 20.29 | 124.79 ± 14.03 | 128.93 ± 25.89 | 138.07 ± 25.14 | 0.056 |
NON | 4.79 ± 1.05 | 4.85 ± 1.48 | 4.82 ± 0.65 | 4.81 ± 0.85 | 4.54 ± 0.98 | 0.912 |
MYV | 8.3 (6.5, 8.9) | 8.7 (6.8, 9.8) | 8.6 (8.5, 9.4) | 7.5 (6.6, 8.25) | 5.05 (4.35, 6.25) | <0.001 |
WMF | 5.2 (4.8, 5.9) | 5.8 (5.25, 6.4) | 5.2 (5.1, 5.6) | 4.9 (4.7, 5.3) | 4.45 (4.27, 4.65) | <0.001 |
GMF | 93.08 ± 1.55 | 93.26 ± 1.78 | 93.07 ± 1.33 | 92.92 ± 1.5 | 93.03 ± 1.71 | 0.929 |
CSFF | 13 (9.9, 14.2) | 12.8 (10.5, 14) | 12.1 (9.9, 14.3) | 13.2 (9.55, 14.15) | 12.2 (8.43, 14.93) | 0.992 |
NONF | 0.72 (0.65, 0.82) | 0.8 (0.61, 1) | 0.72 (0.7, 0.8) | 0.76 (0.68, 0.84) | 0.73 (0.68, 0.8) | 0.889 |
MYF | 1.1 (0.9, 1.4) | 1.3 (1.1, 1.4) | 1.21 (1.11, 1.4) | 1 (0.9, 1.2) | 0.8 (0.78, 0.83) | <0.001 |
WMV, volume of white matter; GMV, volume of gray matter; CSF, cerebrospinal fluid; NON, non-WM/GM/CSF; MYV, myelination volume; WMF, white matter fraction; GMF, gray matter fraction; CSFF, cerebrospinal fluid fraction; NONF, NON fraction; MYF, myelin fraction.