Figure 1. Incidence Rates of Hospitalization for Severe Acute Liver Injury (ALI) for Group 1 and 2 Medications.

Age- and sex-adjusted incidence rates (solid circles), reported with 95% CIs (whiskers), were assessed among patients without preexisting liver or biliary disease and after censoring for incident diagnoses of liver or biliary diseases or other conditions that might precipitate findings consistent with severe ALI. Colors represent the categories of likelihood to cause severe ALI based on the number of published case reports on the medication’s hepatotoxicity. Amox indicates amoxicillin.