Fig. 1.

Schema represents TNCs potentiating β-lactam antibiotics to treat mice with MRSA-induced pneumonia. (a) Schematic of the MRSA-induced pneumonia model, the nebulization treatment using TNCs that potentiate β-lactam antibiotics, and the potentiating mechanism of β-lactam antibiotics by TNCs. (b) High-resolution transmission electron microscope (HR-TEM) image of the TNCs. Scale bar, 20 nm. (c) Size distribution of TNCs measured from the HR-TEM image. (d) Types and proportions of ingredients that make up TNCs using high-performance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry (HPLC-MS-MS). Catechin (CA), Gallocatechin (GC), Catechin gallate (CG), Gallocatechin gallate (GCG), Epicatechin (EC), Epigallocatechin (EGC), Epicatechin gallate (ECG), Epigallocatechin gallate (EGCG).