Fig. 5.
TNCs enhance antibiotic therapy in vivo. (a) Schematic of the infection and treatment protocol. (b) Pneumonitis treatment diagram for mice. (c) CFU of MRSA in infected lungs after treatment with PBS (control), Van, TNCs, Amo and TNCs–Amo. (d) Survival rate (n = 10) of mice inoculated intratracheally with 5 × 108 CFU of MRSA with the following therapeutics: PBS, Van, TNCs, Amo, and TNCs–Amo. (e) H&E staining images of lungs in mice on day 8. Scale bar (left), 500 μm. Scale bar (right), 50 μm. In c, n = 5 biologically independent experiments. *P < 0.05, ***P < 0.001.