Table 2.

Substrate scope for synthesizing aryl-pyrroloindoles 7 bearing axial and central chirality^a.

^a Reaction conditions: 1 (0.1 mmol), 6 (0.12 mmol), (R)-4a (15 mol%), DCM/EtOAc (4:1 v/v, 5 mL), 20 °C for 10–90 h. Isolated yields were provided and the dr values were determined by ¹H NMR. The ee values referred to those of the major diastereomers and were determined by HPLC analysis on a chiral stationary phase.