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. 2022 May 15;4(1):178–187. doi: 10.1016/j.fmre.2022.04.021

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© 2022 The Authors. Publishing Services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 1 — (a,b) Scanning electron microscope (SEM) images of 3,3′,5,5′-tetramethylbenzidine (TMB)-copper peroxide (CuO₂)@poly(lactic-co-glycolic acid) (PLGA) (TCP) and TCP@red blood cell membrane (RBCM) (TCPR) nanoparticles (NPs). (c) Hydrodynamic size distribution of TCPR NP solution (polydispersity index: 0.258). (d) X-ray photoelectron spectroscopy (XPS) survey spectrum. (e) Cu 2p XPS spectra at high resolution. Ultraviolet (UV)–visible (Vis)–near-infrared (NIR) absorption spectra of (f) KMnO₄ incubated with PBS (Control), TCPR NPs, and H₂O₂ for detecting the generation of H₂O₂, (g) TCPR NPs at pH 5.5 and 7.4. (h) Absorbance of the released TMB at different time points under pH 5.5 and 7.4. (i) Concentration changes of H₂O₂ with time changes generated by TCPR NPs at pH 6.5 and 5.5 (***p < 0.001, **p < 0.01).