Table 3.
Domain and Attribute Definitions
| Domain | Definition |
|---|---|
| Appearance | Aesthetic factors of a drug product, such as color, markings, form, shape, size, and texture33 |
| Swallowability | Ability to ingest a drug product without gagging or choking56 |
| Palatability | Physical expressions, gestures, or opinions in response to a drug product by organoleptic properties, such as appearance, smell, taste, texture, and mouthfeel, that make it pleasant to ingest13,30,53,56 |
| Handling | Ability to pick up and handle a drug product prior to ingestion42 |
| Attribute | Definition |
| Texture | Surface attributes of a drug product perceptible by means of mechanical, tactile, visual, and auditory receptors44 |
| Form | The way in which a drug product is presented, such as a tablet or capsule57 |
| Size | Overall dimensions or magnitude of a drug product |
| Shape | External form, contours, or outline of a drug product |
| Color | Properties possessed by a drug product of producing different sensations on the eye as a consequence of the way it reflects light |
| Marking | Imprint of coded alphanumeric characters, symbols, and/or shapes on a drug product58 |
| Mouthfeel | Tactile properties perceived from the point a drug product is placed in the mouth to when it is swallowed44 |
| Smell | Perceived or detected odor or scent of a drug product via the nose |
| Taste | Perceived or experienced flavor of a drug product in the mouth |