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. Author manuscript; available in PMC: 2024 Jun 25.
Published in final edited form as: Mucosal Immunol. 2020 Jun 23;14(1):135–143. doi: 10.1038/s41385-020-0306-6

Fig. 5. SI transcellular the paracellular permeability was associated with the development of oral antigen-induced secretory diarrhea.

Fig. 5.

(A) Isc baseline and (B) TER measurements of jejunal segments from OVA-sensitized mice following Vehicle (Saline) or OVA oral challenge (7th challenge) and stratified according to secretory diarrhea development (60 min). OVA-sensitized mice were challenged with OVA (7th Challenge) and evidence of profuse liquid stool (diarrhea-positive) was examined. Following the 60 min diarrhea observation period, jejunal segments were removed and mounted in a Ussing Chamber system and Isc and TER were recorded as described in the Material and Methods section. Data are represented as the mean ± SD, n= 4 - 7 mice per group. **** P < 0.0001, *** P < 0.001, ** P < 0.01, * P < 0.05, ns > 0.05.