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TABLE 1.

Sequences of PNA oligomers and locations of targeted genes relative to the HXB2 numbering system

PNA oligomer Sequence (5′-3′) Position in HIV-1 genome
PNAGag1 CGCTCTCGCACCCAT 790–804
PNAGag2 TCCCTGCTTGCCCAT 894–908
PNAGag3 TCATCATTTCTTCT 1818–1831
PNAPR1 CCAAAGAGTGATTTT 2256–2270
PNAPR2 TCGTTGCCAAAGAGT 2262–2276
PNAPR3 ATCATCTGCTCCTGT 2328–2342
PNAPR4 CCCCCTATCATTTTT 2384–2398
PNART1 TTTTACTGGTACAGT 2568–2582
PNART2 CTGTCAATGGCCATT 2617–2631
PNART3 ATTTTCAGGCCCAA 2698–2711
PNART4 CTGTCTTTTTTCTTT 2738–2752
PNART5 ATTGTACTGATATCT 2976–2990
PNART6 AATCATCCATGTATT 3094–3108
PNART7 TGCTGCCCTATTTCT 3128–3142
PNART8 ATTGACAGTCCAGCT 3300–3314
PNARH1 TGTGCTGGTACCCAT 4151–4165
PNAINT1 TAGCCATTGCTCTCC 4285–4299
PNAINT2 TCTACTTGTCCATGC 4379–4393
PNAINT3 CTTCCTGCTAATTTT 4535–4549
PNAINT4 CCCCCAATCCCCCCT 4793–4807
PNAINT5 AATTTTGAATTTTT 4883–4896
PNAINT6 TTGCTGGTCCTTTCC 4933–4947