TABLE 2.
HIV-1 virion production from PHA-PBMC infected with clinical MDR isolates and cultured in the absence or presence of 60 μM PNAPR2
| MDR isolate no. | Result of MAGI-CCR5 assaya
|
|
|---|---|---|
| No PNAPR2 | 60 μM PNAPR2 | |
| 1 | 467.7 ± 138.6 | 12.7 ± 4.2 (97.3) |
| 2 | 486.7 ± 112.0 | 4.7 ± 5.5 (99.0) |
| 3 | 210.0 ± 16.10 | 1.3 ± 0.6 (99.4) |
| 4 | 589.7 ± 32.10 | 7.7 ± 4.2 (98.7) |
| 5 | 214.0 ± 142.6 | 5.7 ± 1.5 (97.4) |
| 6 | 219.7 ± 25.20 | 3.7 ± 1.5 (98.3) |
| 7 | 208.3 ± 96.70 | 2.0 ± 1.0 (99.0) |
a
Results are shown as the mean numbers ± SDs of blue cells per well. Values in parentheses are the mean percent reductions.