Table 4.

AUC Analysis for Conversion to CAC >0 Among Older Persons, Stratified by Sex

	All (N = 815)			Men (n = 270)			Women (n = 545)
	C-Statistic	ΔC-Statistic	ΔC-Statistic P Value	C-Statistic	ΔC-Statistic	ΔC-Statistic P Value	C-Statistic	ΔC-Statistic	ΔC-Statistic P Value
Demographics
Age, sex, race	0.567	-	-	0.563	-	-	0.557	-	-
Traditional risk factors
Traditional risk factorsa	0.600	+0.033	0.05	0.609	+0.042	0.09	0.601	+0.044	0.08
Pooled cohort equations ASCVD risk score	0.567	0.000	0.94	0.524	−0.039	0.49	0.562	+0.005	0.80
Novel risk factors and imaging
Individual risk factors + urine albumin-creatinine ratio	0.604	+0.037	0.02	0.615	+0.052	0.04	0.601	+0.044	0.07
Individual risk factors + carotid plaque	0.605	+0.038	0.02	0.614	+0.051	0.05	0.605	+0.048	0.04
Individual risk factors + TAC	0.609	+0.042	0.01	0.611	+0.048	0.08	0.611	+0.054	0.04
Individual risk factors + urine albumin-creatinine ratio + carotid plaque	0.609	+0.042	0.01	0.617	+0.054	0.03	0.609	+0.052	0.03
Individual risk factors + urine albumin-creatinine ratio + TAC	0.613	+0.046	0.006	0.617	+0.054	0.05	0.611	+0.054	0.04
Individual risk factors + carotid plaque + TAC	0.614	+0.047	0.007	0.618	+0.055	0.03	0.614	+0.057	0.08
Individual risk factors + urine albumin-creatinine ratio + carotid plaque + TAC	0.614	+0.047	0.004	0.618	+0.055	0.04	0.614	+0.057	0.03

All models included age, sex, and race.

ASCVD = atherosclerotic cardiovascular disease; AUC = area under the curve; CAC = coronary artery calcium; TAC = thoracic aortic calcification.

^aCigarette smoking, systolic blood pressure, diastolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, blood glucose, triglycerides, waist circumference, antihypertensive medication, lipid-lowering medication, glucose-lowering medication.